Martinez sat out the previous two games because of illness but had been expected to return Wednesday. He's hitting .308 with nine homers and 28 RBIs.
Manager Alex Cora said he was hesitant to play Martinez in Thursday's finale, citing Toronto's artificial surface and the early 12:37 p.m. gametime. The Red Sox begin a three-game series at Houston on Friday.
The Blue Jays are fortunate to not have to face Martinez: He's got 13 homers and 41 RBIs in 40 career games against Toronto.
Martinez went hitless in nine straight at-bats before his absence. He's homered five times in his past 10 games following a 15-game drought.
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