Osaghae finished with 13 points and 10 rebounds. Eric Lovett added 14 points, Isaiah Banks scored 13 and Cameron Corcoran had 12 for the Panthers.
Florida International (2-2) is averaging 104 points per game in its two wins this season.
Hugo Ferreira had 12 points for the Vikings (1-4) and Craig Beaudion scored 11.
Florida International plays Eastern Kentucky on Friday. Cleveland State plays UNC Wilmington on Friday.
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